Optimal Treatment Plans for Volumetric Modulated Arc Therapy (VMAT) Using Branch-and-Price
Tarih ve Saat
16 Ekim 2017 - 14:00
YerMühendislik Binası A-511
Title: Optimal Treatment Plans for Volumetric Modulated Arc Therapy (VMAT) Using Branch-and-Price
Abstract: Radiation therapy uses high-energy radiation and kill cancer cells. Its success depends on the ability to deliver the proper amount of radiation to a tumor while sparing surrounding normal tissues. Radiation can be delivered continuously during VMAT, which is an external radiation therapy technique, because the gantry of the linear accelerator (linac) may rotate on one or more arcs. Linac is also equipped with a multileaf collimator (MLC) that shapes the radiation. These properties make VMAT powerful in obtaining high conformal plans in terms of dose distribution with short treatment times. However, the apertures that composed by the MLC are interdependent, which makes planning hard. In this talk, we propose a mixed integer linear programming model and a branch-and-price algorithm for optimal treatment planning.
Biography: Pınar Dursun is currently a PhD candidate and a research assistant in Department of Industrial Engineering at Boğaziçi University. She holds B.Sc. degree in Mathematical Engineering (2006) and M.Sc. degree in Industrial Engineering (2009) from Istanbul Technical University. Her dissertation focuses on the determination of optimum radiation therapy treatment plans.